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Type C botulinum toxin causes degeneration of motoneurons in vivo

All botulinum toxins (BoNTs, types A–G) inhibit synaptic transmitter release from motoneurons, and thus result in respiratory arrest and death. Rapid treatment with anti-BoNT antibodies can prevent progression, but recovery still requires weeks on a ventilator. Even after recovery, there is a potent...

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Bibliografiske detaljer
Udgivet i:Neuroreport
Main Authors: Zhao, Li-Chun, Yang, Bo, Wang, Rengang, Lipton, Stuart A., Zhang, Dongxian
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351749/
https://ncbi.nlm.nih.gov/pubmed/19907349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0b013e328330dcca
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