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Type C botulinum toxin causes degeneration of motoneurons in vivo

All botulinum toxins (BoNTs, types A–G) inhibit synaptic transmitter release from motoneurons, and thus result in respiratory arrest and death. Rapid treatment with anti-BoNT antibodies can prevent progression, but recovery still requires weeks on a ventilator. Even after recovery, there is a potent...

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Detalhes bibliográficos
Publicado no:Neuroreport
Main Authors: Zhao, Li-Chun, Yang, Bo, Wang, Rengang, Lipton, Stuart A., Zhang, Dongxian
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351749/
https://ncbi.nlm.nih.gov/pubmed/19907349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0b013e328330dcca
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