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Type C botulinum toxin causes degeneration of motoneurons in vivo

All botulinum toxins (BoNTs, types A–G) inhibit synaptic transmitter release from motoneurons, and thus result in respiratory arrest and death. Rapid treatment with anti-BoNT antibodies can prevent progression, but recovery still requires weeks on a ventilator. Even after recovery, there is a potent...

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Foilsithe in:Neuroreport
Main Authors: Zhao, Li-Chun, Yang, Bo, Wang, Rengang, Lipton, Stuart A., Zhang, Dongxian
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351749/
https://ncbi.nlm.nih.gov/pubmed/19907349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0b013e328330dcca
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