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Quercetin prevents spinal motor neuron degeneration induced by chronic excitotoxic stimulus by a sirtuin 1-dependent mechanism

BACKGROUND: Excitotoxicity is a mechanism of foremost importance in the selective motor neuron degeneration characteristic of motor neuron disorders. Effective therapeutic strategies are an unmet need for these disorders. Polyphenols, such as quercetin and resveratrol, are plant-derived compounds th...

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Podrobná bibliografie
Vydáno v:Transl Neurodegener
Hlavní autoři: Lazo-Gomez, Rafael, Tapia, Ricardo
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697078/
https://ncbi.nlm.nih.gov/pubmed/29201361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-017-0102-8
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