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Quercetin prevents spinal motor neuron degeneration induced by chronic excitotoxic stimulus by a sirtuin 1-dependent mechanism

BACKGROUND: Excitotoxicity is a mechanism of foremost importance in the selective motor neuron degeneration characteristic of motor neuron disorders. Effective therapeutic strategies are an unmet need for these disorders. Polyphenols, such as quercetin and resveratrol, are plant-derived compounds th...

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Bibliografiske detaljer
Udgivet i:Transl Neurodegener
Main Authors: Lazo-Gomez, Rafael, Tapia, Ricardo
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697078/
https://ncbi.nlm.nih.gov/pubmed/29201361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-017-0102-8
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