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Histone deacetylases and their role in motor neuron degeneration

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, characterized by the progressive loss of motor neurons. The cause of this selective neuronal death is unknown, but transcriptional dysregulation is recently emerging as an important factor. The physical substrate for the regul...

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Detalhes bibliográficos
Main Authors: Lazo-Gómez, Rafael, Ramírez-Jarquín, Uri N., Tovar-y-Romo, Luis B., Tapia, Ricardo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852234/
https://ncbi.nlm.nih.gov/pubmed/24367290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2013.00243
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