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Histone deacetylases and their role in motor neuron degeneration

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, characterized by the progressive loss of motor neurons. The cause of this selective neuronal death is unknown, but transcriptional dysregulation is recently emerging as an important factor. The physical substrate for the regul...

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Main Authors: Lazo-Gómez, Rafael, Ramírez-Jarquín, Uri N., Tovar-y-Romo, Luis B., Tapia, Ricardo
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852234/
https://ncbi.nlm.nih.gov/pubmed/24367290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2013.00243
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