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Delayed administration of VEGF rescues spinal motor neurons from death with a short effective time frame in excitotoxic experimental models in vivo

VEGF (vascular endothelial growth factor) prevents neuronal death in different models of ALS (amyotrophic lateral sclerosis), but few studies have addressed the efficacy of VEGF to protect motor neurons after the onset of symptoms, a critical point when considering VEGF as a potential therapeutic ta...

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Autori principali: Tovar-y-Romo, Luis B, Tapia, Ricardo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Neurochemistry 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314302/
https://ncbi.nlm.nih.gov/pubmed/22369757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/AN20110057
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