Enhanced activation of cellular AMPK by dual-small molecule treatment: AICAR and A769662

AMP-activated protein kinase (AMPK) is a key cellular energy sensor and regulator of metabolic homeostasis. Activation of AMPK provides beneficial outcomes in fighting against metabolic disorders such as insulin resistance and type 2 diabetes. Currently, there is no allosteric AMPK activator availab...

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Main Authors: Ducommun, Serge, Ford, Rebecca J., Bultot, Laurent, Deak, Maria, Bertrand, Luc, Kemp, Bruce E., Steinberg, Gregory R., Sakamoto, Kei
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Physiological Society 2014
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Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948978/
https://ncbi.nlm.nih.gov/pubmed/24425763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00672.2013
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