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Fanconi anemia protein FANCD2 is activated by AICAR, a modulator of AMPK and cellular energy metabolism
FANCD2 is a pivotal molecule in the pathogenesis of Fanconi anemia (FA), an autosomal recessive human syndrome with diverse clinical phenotypes, including cancer predisposition, short stature, and hematological abnormalities. In our previous study, we detected the functional association of FANC prot...
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| Publicado no: | FEBS Open Bio |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5292659/ https://ncbi.nlm.nih.gov/pubmed/28174693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12185 |
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