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Fanconi anemia protein FANCD2 is activated by AICAR, a modulator of AMPK and cellular energy metabolism

FANCD2 is a pivotal molecule in the pathogenesis of Fanconi anemia (FA), an autosomal recessive human syndrome with diverse clinical phenotypes, including cancer predisposition, short stature, and hematological abnormalities. In our previous study, we detected the functional association of FANC prot...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Chun, Min Jeong, Choi, Hana, Jun, Dong Wha, Kim, Sunshin, Kim, Yong‐Nyun, Kim, Soo‐Youl, Lee, Chang‐Hun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292659/
https://ncbi.nlm.nih.gov/pubmed/28174693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12185
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