Transcription factors IIS and IIF enhance transcription efficiency by differentially modifying RNA polymerase pausing dynamics

Transcription factors IIS (TFIIS) and IIF (TFIIF) are known to stimulate transcription elongation. Here, we use a single-molecule transcription elongation assay to study the effects of both factors. We find that these transcription factors enhance overall transcription elongation by reducing the lif...

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Autori principali: Ishibashi, Toyotaka, Dangkulwanich, Manchuta, Coello, Yves, Lionberger, Troy A., Lubkowska, Lucyna, Ponticelli, Alfred S., Kashlev, Mikhail, Bustamante, Carlos
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948276/
https://ncbi.nlm.nih.gov/pubmed/24550488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401611111
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