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H(2)O(2)-dependent substrate oxidation by an engineered diiron site in a bacterial hemerythrin

The O(2)-binding carboxylate-bridged diiron site in DcrH-Hr was engineered in an effort to perform the H(2)O(2)-dependent oxidation of external substrates. A His residue was introduced near the diiron site in place of a conserved residue, Ile119. The I119H variant promotes the oxidation of guaiacol...

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Hlavní autoři: Okamoto, Yasunori, Onoda, Akira, Sugimoto, Hiroshi, Takano, Yu, Hirota, Shun, Kurtz, Donald M., Shiro, Yoshitsugu, Hayashi, Takashi
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947700/
https://ncbi.nlm.nih.gov/pubmed/24400317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc48108e
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