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UV Resonance Raman Characterization of a Substrate Bound to Human Indoleamine 2,3-Dioxygenase 1
Human indoleamine 2,3-dioxygenase 1 (IDO) is a heme enzyme that catalyzes the first reaction of the main metabolic pathway of L-tryptophan (Trp) to produce N-formylkynurenin. The reaction involves cleavage of the C(2)=C(3) bond in the Trp indole ring and insertion of two atomic oxygens from the iron...
Guardat en:
| Publicat a: | Biophys J |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Biophysical Society
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6712549/ https://ncbi.nlm.nih.gov/pubmed/31405517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.07.017 |
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