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Simple and efficient CRISPR/Cas9-mediated targeted mutagenesis in Xenopus tropicalis
We have assessed the efficacy of the recently developed CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR-associated) system for genome modification in the amphibian Xenopus tropicalis. As a model experiment, targeted mutations of the tyrosinase gene were verified, showing...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3947545/ https://ncbi.nlm.nih.gov/pubmed/24123613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22720 |
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