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Biallelic genome modification in F(0 )Xenopus tropicalis embryos using the CRISPR/Cas system

Gene inactivation is an important tool for correlation of phenotypic and genomic data, allowing researchers to infer normal gene function based on the phenotype when the gene function is impaired. New and better approaches are needed to overcome the shortfalls of existing methods for any significant...

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Autors principals: Blitz, Ira L., Biesinger, Jacob, Xie, Xiaohui, Cho, Ken W.Y.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039559/
https://ncbi.nlm.nih.gov/pubmed/24123579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22719
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