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DNase-seq to study chromatin accessibility in early Xenopus tropicalis embryos
Transcriptional regulatory elements are typically found in relatively nucleosome-free genomic regions, often referred to as “open chromatin.” DNase I can digest nucleosome-depleted DNA (presumably bound by transcription factors), but DNA in nucleosomes or higher-order chromatin fibers is less access...
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| Pubblicato in: | Cold Spring Harb Protoc |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6556395/ https://ncbi.nlm.nih.gov/pubmed/30131367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/pdb.prot098335 |
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