Functional analysis of thyroid hormone receptor beta in Xenopus tropicalis founders using CRISPR-Cas

Amphibians provide an ideal model to study the actions of thyroid hormone (TH) in animal development because TH signaling via two TH receptors, TRα and TRβ, is indispensable for amphibian metamorphosis. However, specific roles for the TRβ isoform in metamorphosis are poorly understood. To address th...

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Bibliographische Detailangaben
Veröffentlicht in:Biol Open
Hauptverfasser: Sakane, Yuto, Iida, Midori, Hasebe, Takashi, Fujii, Satoshi, Buchholz, Daniel R., Ishizuya-Oka, Atsuko, Yamamoto, Takashi, Suzuki, Ken-ichi T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829506/
https://ncbi.nlm.nih.gov/pubmed/29358165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.030338
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