Functional analysis of thyroid hormone receptor beta in Xenopus tropicalis founders using CRISPR-Cas

Amphibians provide an ideal model to study the actions of thyroid hormone (TH) in animal development because TH signaling via two TH receptors, TRα and TRβ, is indispensable for amphibian metamorphosis. However, specific roles for the TRβ isoform in metamorphosis are poorly understood. To address th...

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Bibliografiske detaljer
Udgivet i:Biol Open
Main Authors: Sakane, Yuto, Iida, Midori, Hasebe, Takashi, Fujii, Satoshi, Buchholz, Daniel R., Ishizuya-Oka, Atsuko, Yamamoto, Takashi, Suzuki, Ken-ichi T.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829506/
https://ncbi.nlm.nih.gov/pubmed/29358165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.030338
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