Simple and efficient CRISPR/Cas9-mediated targeted mutagenesis in Xenopus tropicalis

We have assessed the efficacy of the recently developed CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR-associated) system for genome modification in the amphibian Xenopus tropicalis. As a model experiment, targeted mutations of the tyrosinase gene were verified, showing...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Nakayama, Takuya, Fish, Margaret B., Fisher, Marilyn, Oomen-Hajagos, Jamina, Thomsen, Gerald H., Grainger, Robert M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947545/
https://ncbi.nlm.nih.gov/pubmed/24123613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22720
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы