USP22 Regulates Oncogenic Signaling Pathways to Drive Lethal Cancer Progression

Increasing evidence links deregulation of the USP22 deubitiquitylase to cancer development and progression in a select group of tumor types, but its specificity and underlying mechanisms of action are not well-defined. Here we show that USP22 is a critical promoter of lethal tumor phenotypes that ac...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Schrecengost, Randy S, Dean, Jeffry L, Goodwin, Jonathan F, Schiewer, Matthew J, Urban, Mark W, Stanek, Timothy J, Sussman, Robyn T, Hicks, Jessica L, Birbe, Ruth C, Draganova-Tacheva, Rossitza A, Visakorpi, Tapio, DeMarzo, Angelo M, McMahon, Steven B, Knudsen, Karen E
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947329/
https://ncbi.nlm.nih.gov/pubmed/24197134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1954
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki