Contributions of thrombin targets to tissue factor-dependent metastasis in hyperthrombotic mice

BACKGROUND: Tumor cell tissue factor (TF)-initiated coagulation supports hematogenous metastasis by fibrin formation, platelet activation, and monocyte/macrophage recruitment. Recent studies identified host anticoagulant mechanisms as a major impediment for successful hematogenous tumor cell metasta...

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Hlavní autoři: Yokota, Naho, Zarpellon, Alessandro, Chakrabarty, Sagarika, Bogdanov, Vladimir Y., Gruber, András, Castellino, Francis J., Mackman, Nigel, Ellies, Lesley G., Weiler, Hartmut, Ruggeri, Zaverio M., Ruf, Wolfram
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947224/
https://ncbi.nlm.nih.gov/pubmed/24175924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12442
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