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P2X7 receptor signaling contributes to tissue factor–dependent thrombosis in mice

Thrombosis is initiated by tissue factor (TF), a coagulation cofactor/receptor expressed in the vessel wall, on myeloid cells, and on microparticles (MPs) with variable procoagulant activity. However, the molecular pathways that generate prothrombotic TF in vivo are poorly defined. The oxidoreductas...

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Hlavní autoři: Furlan-Freguia, Christian, Marchese, Patrizia, Gruber, András, Ruggeri, Zaverio M., Ruf, Wolfram
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127437/
https://ncbi.nlm.nih.gov/pubmed/21670495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI46129
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