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Tissue factor prothrombotic activity is regulated by integrin-arf6 trafficking

OBJECTIVE: Coagulation initiation by tissue factor (TF) is regulated by cellular inhibitors, cell surface availability of procoagulant phosphatidylserine (PS) and thiol-disulfide exchange. How these mechanisms contribute to keeping TF in a non-coagulant state and to generating prothrombotic TF remai...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Rothmeier, Andrea S., Marchese, Patrizia, Langer, Florian, Kamikubo, Yuichi, Schaffner, Florence, Cantor, Joseph, Ginsberg, Mark H., Ruggeri, Zaverio M., Ruf, Wolfram
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501484/
https://ncbi.nlm.nih.gov/pubmed/28495929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309315
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