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Hematopoietic Tissue Factor–Protease-Activated Receptor 2 Signaling Promotes Hepatic Inflammation and Contributes to Pathways of Gluconeogenesis and Steatosis in Obese Mice

Failure to inhibit hepatic gluconeogenesis is a major mechanism contributing to fasting hyperglycemia in type 2 diabetes and, along with steatosis, is the hallmark of hepatic insulin resistance. Obesity is associated with chronic inflammation in multiple tissues, and hepatic inflammation is mechanis...

詳細記述

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書誌詳細
出版年:Am J Pathol
主要な著者: Wang, Jing, Chakrabarty, Sagarika, Bui, Quyen, Ruf, Wolfram, Samad, Fahumiya
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Investigative Pathology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305186/
https://ncbi.nlm.nih.gov/pubmed/25476527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.10.008
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