Unraveling Mechanism and Significance of Thrombin Binding to Platelet Glycoprotein Ib

Eitemau Tebyg

• Binding of α-thrombin to surface-anchored platelet glycoprotein Ibα sulfotyrosines through a two-site mechanism involving exosite I
  gan: Zarpellon, Alessandro, et al.
  Cyhoeddwyd: (2011)
• Genetic deletion of platelet Glycoprotein Ib alpha but not its extracellular domain protects from atherosclerosis
  gan: Koltsova, Ekaterina K., et al.
  Cyhoeddwyd: (2014)
• 14-3-3 proteins in platelet biology and glycoprotein Ib-IX signaling
  gan: Chen, Yunfeng, et al.
  Cyhoeddwyd: (2018)
• Signaling-mediated cooperativity between glycoprotein Ib-IX and protease-activated receptors in thrombin-induced platelet activation
  gan: Estevez, Brian, et al.
  Cyhoeddwyd: (2016)
• High-affinity alpha-thrombin binding to platelet glycoprotein Ib alpha: identification of two binding domains.
  gan: Gralnick, H R, et al.
  Cyhoeddwyd: (1994)