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Structure and Function of the CSL-KyoT2 Corepressor Complex – a Negative Regulator of Notch Signaling

Notch refers to a highly conserved cell-to-cell signaling pathway with essential roles in embryonic development and tissue maintenance. Dysfunctional signaling causes human disease, highlighting the importance of pathway regulation. Notch signaling ultimately results in the activation of target gene...

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Autors principals: Collins, Kelly J., Yuan, Zhenyu, Kovall, Rhett A.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947186/
https://ncbi.nlm.nih.gov/pubmed/24290140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.10.010
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