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Structure and Function of the CSL-KyoT2 Corepressor Complex – a Negative Regulator of Notch Signaling

Notch refers to a highly conserved cell-to-cell signaling pathway with essential roles in embryonic development and tissue maintenance. Dysfunctional signaling causes human disease, highlighting the importance of pathway regulation. Notch signaling ultimately results in the activation of target gene...

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Detalhes bibliográficos
Main Authors: Collins, Kelly J., Yuan, Zhenyu, Kovall, Rhett A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947186/
https://ncbi.nlm.nih.gov/pubmed/24290140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.10.010
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