Characterization of Defects in Ion Transport and Tissue Development in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)-Knockout Rats

Animal models for cystic fibrosis (CF) have contributed significantly to our understanding of disease pathogenesis. Here we describe development and characterization of the first cystic fibrosis rat, in which the cystic fibrosis transmembrane conductance regulator gene (CFTR) was knocked out using a...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Tuggle, Katherine L., Birket, Susan E., Cui, Xiaoxia, Hong, Jeong, Warren, Joe, Reid, Lara, Chambers, Andre, Ji, Diana, Gamber, Kevin, Chu, Kengyeh K., Tearney, Guillermo, Tang, Li Ping, Fortenberry, James A., Du, Ming, Cadillac, Joan M., Bedwell, David M., Rowe, Steven M., Sorscher, Eric J., Fanucchi, Michelle V.
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2014
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946746/
https://ncbi.nlm.nih.gov/pubmed/24608905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091253
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