SPHINGOSINE-1-PHOSPHATE IN CHRONIC INTESTINAL INFLAMMATION AND CANCER

Sphingosine-1-phosphate (S1P), a pleiotropic bioactive lipid mediator, and the kinase that produces it have now emerged as key regulators of numerous cellular processes involved in inflammation and cancer. Here, we review the importance of S1P in colitis and colitis-associated cancer (CAC) and discu...

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Bibliographic Details
Main Authors: Nagahashi, Masayuki, Hait, Nitai C., Maceyka, Michael, Avni, Dorit, Takabe, Kazuaki, Milstien, Sheldon, Spiegel, Sarah
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946530/
https://ncbi.nlm.nih.gov/pubmed/24210073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbior.2013.10.001
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