SPHINGOSINE-1-PHOSPHATE IN CHRONIC INTESTINAL INFLAMMATION AND CANCER

Sphingosine-1-phosphate (S1P), a pleiotropic bioactive lipid mediator, and the kinase that produces it have now emerged as key regulators of numerous cellular processes involved in inflammation and cancer. Here, we review the importance of S1P in colitis and colitis-associated cancer (CAC) and discu...

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Autori principali: Nagahashi, Masayuki, Hait, Nitai C., Maceyka, Michael, Avni, Dorit, Takabe, Kazuaki, Milstien, Sheldon, Spiegel, Sarah
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946530/
https://ncbi.nlm.nih.gov/pubmed/24210073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbior.2013.10.001
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