Spinster 2, a sphingosine-1-phosphate transporter, plays a critical role in inflammatory and autoimmune diseases

Sphingosine 1-phosphate (S1P) is a pleiotropic bioactive sphingolipid metabolite that regulates numerous processes important for immune responses. S1P is made within cells and must be transported out of cells to exert its effects through activation of 5 specific cell surface GPCRs in an autocrine or...

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Bibliografische gegevens
Gepubliceerd in:FASEB J
Hoofdauteurs: Donoviel, Michael S., Hait, Nitai C., Ramachandran, Subramaniam, Maceyka, Michael, Takabe, Kazuaki, Milstien, Sheldon, Oravecz, Tamas, Spiegel, Sarah
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Federation of American Societies for Experimental Biology 2015
Onderwerpen:
Research Communication
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653056/
https://ncbi.nlm.nih.gov/pubmed/26324848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-274936
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