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Spinster 2, a sphingosine-1-phosphate transporter, plays a critical role in inflammatory and autoimmune diseases

Sphingosine 1-phosphate (S1P) is a pleiotropic bioactive sphingolipid metabolite that regulates numerous processes important for immune responses. S1P is made within cells and must be transported out of cells to exert its effects through activation of 5 specific cell surface GPCRs in an autocrine or...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Donoviel, Michael S., Hait, Nitai C., Ramachandran, Subramaniam, Maceyka, Michael, Takabe, Kazuaki, Milstien, Sheldon, Oravecz, Tamas, Spiegel, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653056/
https://ncbi.nlm.nih.gov/pubmed/26324848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-274936
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