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The Chaperone Protein SmgGDS Interacts with Small GTPases Entering the Prenylation Pathway by Recognizing the Last Amino Acid in the CAAX Motif

Ras family small GTPases localize at the plasma membrane, where they can activate oncogenic signaling pathways. Understanding the mechanisms that promote membrane localization of GTPases will aid development of new therapies to inhibit oncogenic signaling. We previously reported that SmgGDS splice v...

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書誌詳細
主要な著者: Schuld, Nathan J., Vervacke, Jeffrey S., Lorimer, Ellen L., Simon, Nathan C., Hauser, Andrew D., Barbieri, Joseph T., Distefano, Mark D., Williams, Carol L.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945348/
https://ncbi.nlm.nih.gov/pubmed/24415755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.527192
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