Promyelocytic Leukemia Protein Interacts with the Apoptosis-associated Speck-like Protein to Limit Inflammasome Activation

The apoptosis-associated speck-like protein containing a caspase-activating recruitment domain (ASC) is an essential component of several inflammasomes, multiprotein complexes that regulate caspase-1 activation and inflammation. We report here an interaction between promyelocytic leukemia protein (P...

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Detalhes bibliográficos
Main Authors: Dowling, Jennifer K., Becker, Christine E., Bourke, Nollaig M., Corr, Sinead C., Connolly, Dympna J., Quinn, Susan R., Pandolfi, Paolo P., Mansell, Ashley, O'Neill, Luke A. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945309/
https://ncbi.nlm.nih.gov/pubmed/24407287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.539692
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