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The GOLD Domain-containing Protein TMED1 Is Involved in Interleukin-33 Signaling

The proinflammatory danger signal IL-33, which is released from damaged or dying cells, achieves its effects via the IL-1R family member ST2L. The detection of IL-33 by ST2L initiates downstream signaling pathways that result in the activation of MAPKs and NF-κB. Here, we show that TMED1 associates...

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Detalhes bibliográficos
Main Authors: Connolly, Dympna J., O'Neill, Luke A. J., McGettrick, Anne F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581396/
https://ncbi.nlm.nih.gov/pubmed/23319592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.403899
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