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Purification, crystallization and preliminary X-ray diffraction analysis of the kinase domain of human tousled-like kinase 2

Tousled-like kinases (TLKs) are an evolutionarily conserved family of serine/threonine protein kinases involved in chromatin dynamics, including DNA replication and repair, transcription and chromosome segregation. The two members of the family reported in humans, namely TLK1 and TLK2, localize to t...

詳細記述

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書誌詳細
主要な著者: Garrote, Ana M., Redondo, Pilar, Montoya, Guillermo, Muñoz, Inés G.
フォーマット: Artigo
言語:Inglês
出版事項: International Union of Crystallography 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944701/
https://ncbi.nlm.nih.gov/pubmed/24598926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14002581
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