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Purification, crystallization and preliminary X-ray diffraction analysis of the kinase domain of human tousled-like kinase 2

Tousled-like kinases (TLKs) are an evolutionarily conserved family of serine/threonine protein kinases involved in chromatin dynamics, including DNA replication and repair, transcription and chromosome segregation. The two members of the family reported in humans, namely TLK1 and TLK2, localize to t...

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Detalhes bibliográficos
Main Authors: Garrote, Ana M., Redondo, Pilar, Montoya, Guillermo, Muñoz, Inés G.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944701/
https://ncbi.nlm.nih.gov/pubmed/24598926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14002581
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