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Purification, crystallization and preliminary X-ray diffraction analysis of the kinase domain of human tousled-like kinase 2

Tousled-like kinases (TLKs) are an evolutionarily conserved family of serine/threonine protein kinases involved in chromatin dynamics, including DNA replication and repair, transcription and chromosome segregation. The two members of the family reported in humans, namely TLK1 and TLK2, localize to t...

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Autors principals: Garrote, Ana M., Redondo, Pilar, Montoya, Guillermo, Muñoz, Inés G.
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944701/
https://ncbi.nlm.nih.gov/pubmed/24598926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14002581
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