SUMOylation of RhoGDIα is required for its repression of cyclin D1 expression and anchorage‐independent growth of cancer cells

Selective activation of Rho GTPase cascade requires the release of Rho from RhoGDI (GDP‐dissociation inhibitors) complexes. Our previous studies identified RhoGDIα SUMOylation at Lys‐138 and its function in the regulation of cancer cell invasion. In the current study, we demonstrate that RhoGDIα SUM...

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Main Authors: Cao, Zipeng, Li, Xueyong, Li, Jingxia, Kang, Beipei, Chen, Jingyuan, Luo, Wenjing, Huang, Chuanshu
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2013
主題:
Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943698/
https://ncbi.nlm.nih.gov/pubmed/24342356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.11.006
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