SUMOylation of RhoGDIα is required for its repression of cyclin D1 expression and anchorage‐independent growth of cancer cells

Selective activation of Rho GTPase cascade requires the release of Rho from RhoGDI (GDP‐dissociation inhibitors) complexes. Our previous studies identified RhoGDIα SUMOylation at Lys‐138 and its function in the regulation of cancer cell invasion. In the current study, we demonstrate that RhoGDIα SUM...

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Detalhes bibliográficos
Main Authors: Cao, Zipeng, Li, Xueyong, Li, Jingxia, Kang, Beipei, Chen, Jingyuan, Luo, Wenjing, Huang, Chuanshu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943698/
https://ncbi.nlm.nih.gov/pubmed/24342356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.11.006
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