SUMOylation of RhoGDIα is required for its repression of cyclin D1 expression and anchorage‐independent growth of cancer cells

Selective activation of Rho GTPase cascade requires the release of Rho from RhoGDI (GDP‐dissociation inhibitors) complexes. Our previous studies identified RhoGDIα SUMOylation at Lys‐138 and its function in the regulation of cancer cell invasion. In the current study, we demonstrate that RhoGDIα SUM...

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Hlavní autoři: Cao, Zipeng, Li, Xueyong, Li, Jingxia, Kang, Beipei, Chen, Jingyuan, Luo, Wenjing, Huang, Chuanshu
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2013
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943698/
https://ncbi.nlm.nih.gov/pubmed/24342356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.11.006
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