TLR7 preconditioning induces robust neuroprotection against stroke by a novel type I interferon-mediated mechanism

BACKGROUND AND PURPOSE: Systemic administration of Toll-like receptor 4 (TLR4) and TLR9 agonists prior to cerebral ischemia, have been shown to reduce ischemic injury by reprogramming the brain’s response to stroke. Our goal was to explore the mechanism of TLR induced neuroprotection by determining...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Leung, Philberta Y., Stevens, Susan L., Packard, Amy E.B., Lessov, Nikola S., Yang, Tao, Conrad, Valerie K., van den Dungen, Noortje N.A.M., Simon, Roger P., Stenzel-Poore, Mary P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943206/
https://ncbi.nlm.nih.gov/pubmed/22403050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.111.641522
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items