Poly-ICLC preconditioning protects the blood-brain barrier against ischemic injury in vitro through type I interferon signaling

Preconditioning with a low dose of harmful stimulus prior to injury induces tolerance to a subsequent ischemic challenge resulting in neuroprotection against stroke. Experimental models of preconditioning primarily focus on neurons as the cellular target of cerebral protection while less attention h...

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Main Authors: Gesuete, Raffaella, Packard, Amy E. B., Vartanian, Keri B., Conrad, Valerie K., Stevens, Susan L., Bahjat, Frances R., Yang, Tao, Stenzel-Poore, Mary P.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481200/
https://ncbi.nlm.nih.gov/pubmed/23050645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2012.07946.x
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