TLR9 bone marrow chimeric mice define a role for cerebral TNF in neuroprotection induced by CpG preconditioning

Systemic preconditioning with the TLR9 ligand CpG induces neuroprotection against brain ischemic injury through a tumor necrosis factor (TNF)-dependent mechanism. It is unclear how systemic administration of CpG engages the brain to induce the protective phenotype. To address this, we created TLR9-d...

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Detalhes bibliográficos
Main Authors: Packard, Amy EB, Leung, Philberta Y, Vartanian, Keri B, Stevens, Susan L, Bahjat, Frances R, Stenzel-Poore, Mary P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519417/
https://ncbi.nlm.nih.gov/pubmed/23010947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.140
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