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Cullin-based ubiquitin ligases: Cul3–BTB complexes join the family

Cullin-based E3 ligases target substrates for ubiquitin-dependent degradation by the 26S proteasome. The SCF (Skp1–Cul1–F-box) and ECS (ElonginC–Cul2–SOCS box) complexes are so far the best-characterized cullin-based ligases. Their atomic structure has been solved recently, and several substrates ha...

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Bibliografische gegevens
Hoofdauteurs: Pintard, Lionel, Willems, Andrew, Peter, Matthias
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2004
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC394240/
https://ncbi.nlm.nih.gov/pubmed/15071497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600186
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