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RhoBTB2 is a substrate of the mammalian Cul3 ubiquitin ligase complex
Rhobtb2 is a candidate tumor suppressor located on human chromosome 8p21, a region commonly deleted in cancer. Rhobtb2 is homozygously deleted in 3.5% of primary breast cancers, and gene expression is ablated in ∼50% of breast and lung cancer cell lines. RhoBTB2 is an 83-kD, atypical Rho GTPase of u...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC395845/ https://ncbi.nlm.nih.gov/pubmed/15107402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1177904 |
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