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RhoBTB2 is a substrate of the mammalian Cul3 ubiquitin ligase complex
Rhobtb2 is a candidate tumor suppressor located on human chromosome 8p21, a region commonly deleted in cancer. Rhobtb2 is homozygously deleted in 3.5% of primary breast cancers, and gene expression is ablated in ∼50% of breast and lung cancer cell lines. RhoBTB2 is an 83-kD, atypical Rho GTPase of u...
Shranjeno v:
| izdano v: | Genes Dev |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395845/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15107402/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1177904 |
| Oznake: |
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