Glycosylations in the globular head of the hemagglutinin protein modulate the virulence and antigenic properties of the H1N1 influenza viruses

The global spread of the 2009 pandemic H1N1 (pH1N1) virus in humans increases the likelihood that this influenza virus strain could undergo antigenic drift in the coming years. Previous seasonal H1N1 and H3N2 influenza strains acquired additional glycosylations in the globular head of their hemagglu...

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Auteurs principaux: Medina, Rafael A., Stertz, Silke, Manicassamy, Balaji, Zimmermann, Petra, Sun, Xiangjie, Albrecht, Randy A., Uusi-Kerttula, Hanni, Zagordi, Osvaldo, Belshe, Robert B., Frey, Sharon E., Eggink, Dirk, Tumpey, Terrence M., García-Sastre, Adolfo
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940933/
https://ncbi.nlm.nih.gov/pubmed/23720581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3005996
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