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Transcription could be the key to the selection advantage of mitochondrial deletion mutants in aging

The mitochondrial theory of aging is widely popular but confronted by several apparent inconsistencies. On the one hand, mitochondrial energy production is of central importance to the health and proper functioning of cells, and single-cell studies have shown that mtDNA deletion mutants accumulate i...

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Hlavní autoři: Kowald, Axel, Kirkwood, Thomas B. L.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939916/
https://ncbi.nlm.nih.gov/pubmed/24569805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314970111
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