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Resolving the Enigma of the Clonal Expansion of mtDNA Deletions

Mitochondria are cell organelles that are special since they contain their own genetic material in the form of mitochondrial DNA (mtDNA). Damage and mutations of mtDNA are not only involved in several inherited human diseases but are also widely thought to play an important role during aging. In bot...

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Dettagli Bibliografici
Pubblicato in:Genes (Basel)
Autori principali: Kowald, Axel, Kirkwood, Thomas B.L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867847/
https://ncbi.nlm.nih.gov/pubmed/29495484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9030126
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