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Transcription could be the key to the selection advantage of mitochondrial deletion mutants in aging

The mitochondrial theory of aging is widely popular but confronted by several apparent inconsistencies. On the one hand, mitochondrial energy production is of central importance to the health and proper functioning of cells, and single-cell studies have shown that mtDNA deletion mutants accumulate i...

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מידע ביבליוגרפי
Main Authors: Kowald, Axel, Kirkwood, Thomas B. L.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939916/
https://ncbi.nlm.nih.gov/pubmed/24569805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314970111
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