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Transcription could be the key to the selection advantage of mitochondrial deletion mutants in aging
The mitochondrial theory of aging is widely popular but confronted by several apparent inconsistencies. On the one hand, mitochondrial energy production is of central importance to the health and proper functioning of cells, and single-cell studies have shown that mtDNA deletion mutants accumulate i...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3939916/ https://ncbi.nlm.nih.gov/pubmed/24569805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314970111 |
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