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JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation
Extracellular high-mobility group box (HMGB)1 mediates inflammation during sterile and infectious injury and contributes importantly to disease pathogenesis. The first critical step in the release of HMGB1 from activated immune cells is mobilization from the nucleus to the cytoplasm, a process depen...
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Main Authors: | , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3939889/ https://ncbi.nlm.nih.gov/pubmed/24469805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1316925111 |
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