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ELF4 is critical for induction of type I interferon and the host antiviral response
Induction of type I interferon is a central event of innate immunity, essential for host defense. Here we report that the transcription factor ELF4 is induced by type I interferon and upregulates interferon expression in a feed-forward loop. ELF4 deficiency leads to reduced interferon production, re...
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| Autori principali: | , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3939855/ https://ncbi.nlm.nih.gov/pubmed/24185615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2756 |
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